Database
As part of its curating function, the Global Observatory collects, summarizes, and sorts resources relevant to the ethics and governance of emerging biotechnologies. Use the “Search and Filter” box on the left side of the page to navigate the resources in this database.
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2015-05
Puping Liang , Yanwen Xu , Xiya Zhang , Chenhui Ding , Rui Huang , Zhen Zhang , Jie Lv , Xiaowei Xie , Yuxi Chen , Yujing Li , Ying Sun , Yaofu Bai , Zhou Songyang , Wenbin Ma , Canquan Zhou , Junjiu Huang
This 2015 study describes an experiment that utilized CRISPR/Cas9 to modify human embryos in vitro. These embryos were pre-implantation and nonviable, and the study identified technical difficulties with embryonic CRISPR modification, including poor DNA repair and off-target effects.
2015-04
David Baltimore , Paul Berg , Michael Botchan , Dana Carroll , R. Alta Charo , George Church , Jacob E. Corn , George Q. Daley , Jennifer A. Doudna , Marsha Fenner , Henry T. Greely , Martin Jinek , G. Steven Martin , Edward Penhoet , Jennifer Puck , Samuel H. Sternberg , Jonathan S. Weissman , Keith R. Yamamoto
A collection of prominent scientific researchers call for open discourse on the potential applications of CRISPR/Cas9 to modify the human genome.
2015-04
David Baltimore , Paul Berg
Two of the scientists responsible for the Asilomar conference support a similar voluntary moratorium on human germline genome editing.
2015-03
International Society for Stem Cell Research (ISSCR)
ISSCR released this statement shortly before the publication of CRISPR research on nonviable human embryos. It suggests a moratorium on clinical germline genome editing research.
2015
David Baltimore , Françoise Baylis , Paul Berg , George Q. Daley , Jennifer A. Doudna , Eric S. Lander , Robin Lovell-Badge , Pilar Ossorio , Duanqing Pei , Adrian Thrasher , Ernst-Ludwig Winnacker , Qi Zhou
This statement followed the first three-day International Summit on Human Gene Editing convened by the National Academies of Sciences and Medicine.