The author argues for the extension of the 14-day rule based on potential biomedical and therapeutic applications and the lack of “coherent or persuasive reasons to deny researchers, and through them humanity, the knowledge and the innovation that this will generate” (2021:e66).

Nobel laureate CRISPR-developer Jennifer Doudna discusses two primary ethical concerns surrounding the technology’s use: the need for internationally recognized regulations and the need to ensure that CRISPR-derived treatments are accessible worldwide.

In Nature Biotechnology, Vivien Marx provides a reminder that the children that resulted from He Jiankui’s CRISPR experiments—the twins “Lulu” and “Nana” and a third, younger child, here called “Amy”—are now toddlers.

The authors respond to McCully’s (2021) arguments for extending the 14-day rule to 28 days. They argue that biomedical advances do not justify changing the rule, since the reasoning of the Warnock Committee remains relevant.

In the form of an open letter published in the DIY-biologist and fablab-focused Makery, bioartist and Adam Zaretsky provides an artistic critique of not only the rationale driving the editing and implantation of human embryos, but also the rationale driving bioethics and the proposition of research